AKG: A Supplement to Slow Aging?

The field of natural supplements to conserve or promote good health or as remedies for specific conditions is a complex one. Many of them have long and distinguished traditions and are becoming more popular than ever. That is the basis of Complementary or Integrated Medicine-combining the old (pre-20th century) with modern techniques and science to improve patient outcomes, including the brain-boosting nootropics and new anti-aging solutions.

The sudden meeting of these two approaches has created a problem: there has not been the time or resources to thoroughly investigate how and at what dosage the majority of natural medicines are safe and most effective. That has resulted in doubts, skepticism and at times conflict between the two. AKG is one of the few about which both sides agree. It has been subjected to rigorous and large-scale studies from around the world beginning in the 1970’s.

AKG is a driving link in the whole metabolic process, without which we couldn’t produce energy, healthy new cells or much else. AKG’s function is in forming amino acids, which are the fundamental blocks from which our bodies are built and maintained. It’s an important component of the “Krebs Cycle” or TCA cycle – Tricarboxylic Acid Cycle found in all air-breathing organisms.

AKG is a single molecule produced naturally in the bodies of all animals. As we age our capacity to produce enough for optimum health decreases. That’s what makes this one of the most in-demand supplements today. It was first used by bodybuilders to increase muscle-mass.

For a few years AKG faded from view-until studies showed just what it’s there for. It does help maintain muscle but the point is about why it does-which is a far bigger picture. The answer is probably that it’s a naturally produced agent acting directly along the pre-programmed chemical pathways of the body. That explains why it’s so safe and doesn’t cause adverse side-effects at normal dosage, 300-1000mg a day. Most pharmaceuticals and many natural medicines act on top of those pathways, creating new ones, which can cause conflicts by upsetting the natural balances.

There’s the important difference between supplementing to achieve healthy homeostasis, which is vital to help the body to heal and/or increase performance or using non-innate ones which may suppress immediate symptoms without tackling their cause. These make you feel better – for a while – but allow any underlying problem(s) to increase by being untreated.

AKG also fights the aging process as a major metabolite in the tricarboxylate acid cycle (TCA). By doing that it reduces overall systemic inflammation – a major biomarker of aging by producing more IL-10. Interleukin-10 is vital to the immune system, especially in beating cancers.

That’s very unusual for any energy-booster because normally high energy means a faster metabolism, higher inflammation and, through mTor, a higher chance of cancer. mTor is an important protein of cell structure: too many cells produced too quickly cause abnormalities. AKG doesn’t, it boosts energy, while at the same time reducing overall inflammation because it’s also an antioxidant. (Skand J Gastroenterol, May 2012).

Most notably it fights colon cancer and improves the microbiome of the gut-which is vital to the immune system, digestion and brain function. That makes AKG a Nootropic as well.

Astonishingly AKG has been found to give many of the well-established benefits of a plant-based diet; which is how it encourages good gut bacteria and strengthens the immune system. That results in weight loss, more lean muscle, less fat, lower cholesterol, improved cardio-vascular health and lower inflammation. It’s remarkable-hence the increasing levels of scientific interest and its popularity among customers.

Double Wood Supplements provides an excellent and convenient source of AKG:

Studies:

AKG study first to show “dramatically compressed” morbidity in mammals

Alpha-Ketoglutarate: Physiological Functions and Applications

A metabolite produced by the body increases lifespan and dramatically compresses late-life morbidity in mice

Alpha-Ketoglutarate Overview

Bodybuilding supplement promotes healthy aging and extends life span, at least in mice

By |2021-04-01T18:29:44+00:00April 1st, 2021|

About the Author:

Dr. Ian Hale earned his BA (Honors) in Cultural Studies (English and History) at the University of Portsmouth, before receiving his Teaching License from Bristol University (England). He earned his M.A. in Professional Special Education Studies, which included genetics, neurology and haemotology at Bath Spa University in 2008. He received his Ph.D. (H.C.) in Humanitas at UNESCO in 2006. Prof Hale has guest lectured at Touro Law School, Jewish Law Institute under Prof Samuel L Levine, New York on Neurodiversity. He is the author of bit.ly/2SUT00C and amzn.to./31dlbFc Prof Hale also holds an International Diploma in Integrated Medicine.