Found in many fruits and vegetables is a natural flavonoid called Quercetin. This polyphenol has an abundance of effects conducive to general health.
As more research accrues, the list of quercitin’s prospective benefits grow, indicating quercetin supplements may produce positive effects for health issues ranging from cardiovascular disease to cancer. Moreover, studies have shown significant cognitive benefits from this compound in healthy subjects and those with neurodegenerative diseases.
In consideration of general cardiovascular health, blood pressure plays a significant role. Supplementation with quercetin has shown itself to be an excellent means of reducing blood pressure. Human studies dating back to 1993 have shown flavonoids like Quercetin reduce the incidence and mortality from cardiovascular conditions. (Hertog, 1993)
Regarding quercetin’s role in cancer research, the results show great promise. Although most studies have employed doses that are not clinically realizable, studies using lower-doses have revealed quercetin still delivers anti-tumor, anti-inflammatory, and antioxidant effects. One study proved the chemopreventive effects of a modest dose of quercetin through inhibiting cell cycle progression (Jeong, 2009).
The use of quercetin appears to have multiple positive effects on cognition. Studies have discovered that the antioxidant properties of Quercetin protects neuronal cells from toxicity caused by oxidative stress.
Additionally, research indicates quercetin (like caffeine) functions as an adenosine antagonist. Given this property, there is the potential that it may mitigate both cognitive and physical fatigue. More significant was the finding that quercetin has positive benefits for memory and general learning ability (Priprem, 2008).
The cognitive benefits of quercetin may also extend to the treatment of Alzheimer’s Disease. Studies on animal models have discovered that quercetin supplementation facilitated a reduction in mitochondrial dysfunction and plaque burden (Wang, 2014).
Altogether, quercetin is an excellent supplement for attaining or maintaining overall health. The cardiovascular implications may be greater longevity. The cognitive implications, a stronger memory and capacity to learn. Quercetin is a supplement that may as well have the Classical Latin motto, Mens sana in corpore sano (a healthy mind in a healthy body).
When considering which quercetin supplement to take, one should look towards only those of the highest quality. Double Wood Supplements provides a superb quality quercetin supplement, even including bromelain as an additive to precipitate the absorption of the quercetin. Taking such a supplement at the recommended dosage along with other healthy lifestyle choices is a fine avenue for the improvement of physical and cognitive well-being.
References and Suggested Reading
Priprem A, Watanatorn J, Sutthiparinyanont S, Phachonpai W, Muchimapura S. Anxiety and cognitive effects of quercetin liposomes in rats. Nanomedicine. 2008 Mar;4(1):70-8. doi: 10.1016/j.nano.2007.12.001. Epub 2008 Jan 30. PMID: 18249157.
Jeong, Jae-Hoon et al. Effects of low dose quercetin: cancer cell-specific inhibition of cell cycle progression. Journal of cellular biochemistry vol. 106,1 (2009): 73-82. doi:10.1002/jcb.21977
Hertog MG, Feskens EJ, Hollman PC, Katan MB, Kromhout D. Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study. Lancet. 1993 Oct 23;342(8878):1007-11. doi: 10.1016/0140-6736(93)92876-u. PMID: 8105262.
Wang DM, Li SQ, Wu WL, Zhu XY, Wang Y, Yuan HY. Effects of long-term treatment with quercetin on cognition and mitochondrial function in a mouse model of Alzheimer’s disease. Neurochemistry Research. 2014 Aug;39(8):1533-43. doi: 10.1007/s11064-014-1343-x. Epub 2014 Jun 4. PMID: 24893798.