Coffee: Liver Health and Antidepressant

Coffee has been beloved by more than one intellectual. Bach would drink it by the gallon to supercharge his prolific powers; Balzac would brew gallons of it to churn out literary masterpieces by the dozens; Emanuel Swedenborg, the great mystic and scientist, would indulge heavily in the drink to sustain his research into mechanics, geology, physics, and theology.

More recently, coffee has been found to have health benefits. The evidence, which we will review here, is mixed in some areas, but for the most part tips the scales in favor of moderate coffee consumption, for most people, for a longer and better life.

Like many other plant products, coffee beans contain thousands of bioactive compounds. Broadly speaking, the purported benefits of these molecules together include the attenuation of inflammation and oxidative stress, stimulation of the CNS (yeah, you knew that already), and the prevention of carcinogenesis. There is an inverse relationship between liver cirrhosis and coffee consumption, suggesting that one or more of these compounds protect the liver (Higdon, 2006). It has also been shown to act as preventative against liver fibrosis, HCC, and abnormal liver function (Freedman, 2009). For patients with advanced hepatitis C, regular coffee consumption is associated with slower disease progression. It’s good to note that energy drinks do not exhibit these same positive effects on the liver (Corrao, 2001).

Depression is a public health issue. This epidemic inflicts tremendous suffering upon hundreds of millions of people across the global and, at some point, is bound to affect almost everyone. A study of 50,000 women revealed that at least one cup of coffee a week reduced their risk of depression by 15% and two to three cups a day slashed it by 20 (Ruusunen, 2010). It was found moderate coffee drinkers, men and women, were 45% less likely to commit suicide and heavy drinkers were 53% less likely. By facilitating the production of BDNF, among other things, coffee can quite literally save a person’s life.


Allysian Rise Coffee

Rise Coffee is composed of a synergistic blend of active ingredients in the perfect proportions and optimal potencies to stimulate the production of neuroprotective factors, including BDNF (Brain Derived Neurotrophic Factor), that are vital to learning, memory, and overall brain health. Certified fair trade and organic, Rise releases the robust flavours of 100% Arabica coffee crystals, enhanced with clinically supported natural extracts such as Neurofactor.™

Works Cited and Suggested Reading

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Chaldakov, G.N., Tonchev, A.B., & Aloe, L. (2009). NFG and BDNF: from nerves to adipose tissue, from neurokines to metabokines. Rivista Di Psichiatria, 44(2), 79-87.

Lai, P.L., Naidu, M., Sabaratnam, V., Wong, K.H., David, R.P., Kuppusamy, U.R., Abdullah, N., & Malek, S.N. (2013). Neurotrophic properties of the Lion’s mane medicinal mushroom, Hericium erinaceus (Higher Basidiomycetes) from Malaysia. Int J Med Mushrooms, 15(6), 539- 554.

Mori, K., Inatomi, S., Ouchi, K., Azumi, Y., & Tuchida, T. (2009). Improving effects of the mushroom Yamabushitake (Hericium erinaceus) on mild cognitive impairment: a double-blind placebo-controlled clinical trial.

Mori, K., Obara, Y., Moriya, T., Inatomi, S., & Nakahata, N. (2011). Effects of Hericium erinaceus on amyloid B(25-35) peptide-induced learning and memory deficits in mice. Biomed Res, 32(1), 67-72.

Nagano, M., Shimizu, K., Kondo, R., Hayashi, C., Sato, D., Kitagawa, K., & Ohnuki, K. (2010). Reduction of depression and anxiety by 4 weeks Hericium erinaceus intake. Biomed Res, 31(4), 231-237.

Tuszynski, M.H., & Blesch, A. (2004). Nerve growth factor: from animal models of cholinergic neuronal degeneration to gene therapy in Alzheimer’s disease. Progress In Brain Research, 146, 441-449.

Tuszynski, M.H., Yang, J.H., Barba, D., U, H.S., Bakay, R.A., Pay, M.M., et al. (2015). Nerve growth factor gene therapy: activation of neuronal responses in Alzheimer disease. JAMA Neurology, 72, 1139-1147.

Villoslada, P., & Genain, C.P. (2004). Role of nerve growth factor and other trophic factors in brain inflammation. Progress In Brain Research, 146, 403-414.

Wong, K.H., Naidu, M., David, R.P., Bakar, R., & Sabaratnam, V. (2012). Neuroregenerative potential of lion’s mane mushroom, Hericium erinaceus (Bull.:Fr.) Pers. (higher Basidiomycetes), in the treatment of peripheral nerve injury. Int J Med Mushrooms, 14(5), 427- 446

By |2020-09-23T23:43:33+00:00January 1st, 2020|

About the Author:

Adam Alonzi is a writer, biotechnologist, documentary maker, futurist, inventor, programmer, and author of two obscure novels.